Circulating tumor cells (CTCs) have a characteristic identification in metastasis. In order to monitor, diagnose, and analyze early-stage non-hematologic cancers, these rare cells must be separated from the whole blood with high efficiency. Thus, a microfluidic chip coated with E-selectin and microscopic inclined three-dimensional groove and wave patterns, which increases the probability of cell contact and separates the leukocytes and CTCs even further, is created.
Each year, over two million new cases of skin cancer are diagnosed, which is greater than the combined incidence of cancers of the breast, prostate, lung and colon. Therefore, prevention of skin cancer from the harmful effects of UV remains a priority area of research.
Alzheimer’s is a neurodegenerative disease characterized by the formation of extracellular amyloid-beta (abeta or AB) plaques and intracellular tau plaques. This experiment explores whether the presence of normal tau-441 protein augments AB-42 aggregation.