History of Antibiotic Adaptation Influences Microbial Evolutionary Dynamics During Subsequent Treatment
Antibiotic resistance is a growing healthcare concern whereby bacterial infections are increasingly difficult to eradicate due to their ability to survive antibiotic treatments [1]. There have been reported cases of resistance for nearly every antibiotic we have available [2]. Coupled with the fact that the antibiotic discovery pipeline has slowed over the past few decades [3], there is a dire need to find better treatment strategies using existing antibiotics that can slow or even reverse the development of resistance.