CRISPR Inhibition of Prophage Acquisition in Streptococcus Pyogenes
During evolution, bacteria acquired new traits primarily by horizontal gene transfer (HGT) as a key driving force for expressing novel pathogenic properties, new colonization niches as well as metabolic adaptations [1], [2], [3], [4], [5]. Conjugation, transduction and transformation are the major mechanisms for HGT. The contributions and the impact of each mechanism are variable among species [6].