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Michael Daly



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Expanding the Neuron’s Calcium Signaling Repertoire: Intracellular Calcium Release via Voltage-Induced PLC and IP3R Activation

Neuronal calcium plays a dual role as a charge carrier and as an intracellular messenger. Calcium signals regulate various developmental processes, such as migration in the central nervous system (CNS), growth-cone behavior, dendritic development, and synaptogenesis, but calcium is also involved in apoptosis, and it regulates neurotransmitter release and membrane excitability.

Tab 2

Expanding the Neuron’s Calcium Signaling Repertoire: Intracellular Calcium Release via Voltage-Induced PLC and IP3R Activation

Neuronal calcium plays a dual role as a charge carrier and as an intracellular messenger. Calcium signals regulate various developmental processes, such as migration in the central nervous system (CNS), growth-cone behavior, dendritic development, and synaptogenesis, but calcium is also involved in apoptosis, and it regulates neurotransmitter release and membrane excitability.

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Expanding the Neuron’s Calcium Signaling Repertoire: Intracellular Calcium Release via Voltage-Induced PLC and IP3R Activation

Neuronal calcium plays a dual role as a charge carrier and as an intracellular messenger. Calcium signals regulate various developmental processes, such as migration in the central nervous system (CNS), growth-cone behavior, dendritic development, and synaptogenesis, but calcium is also involved in apoptosis, and it regulates neurotransmitter release and membrane excitability.

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