CACNA1C Gene Regulates Behavioral Strategies in Operant Rule Learning

The ability to learn, to adapt one’s own behavior in order to optimize positive and avoid negative feedback, is central to all living beings. Animals like humans are constantly seeking to infer the (causal) structure of their environment and to predict the outcomes of their actions [1,2], sometimes to a degree that “superstitial beliefs” about environmental contingencies may form [3]. However, since the environment is only partially observable, with an often infinite or exponentially exploding space of possibilities, inferring the optimal course of actions is, in general, a computationally intractable problem.

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