The Nuclear Receptor HIZR-1 Uses Zinc as a Ligand to Mediate Homeostasis in Response to High Zinc

Zinc is an essential nutrient for all life, including plants, animals and microbes, because zinc is involved in many different cellular events. Zn2+ binds tightly to many proteins and thereby contributes to their tertiary structure or catalytic activity [1], and Zn2+ has been proposed to function as a second messenger signaling molecule during synaptic transmission, development, and immune responses. Zinc homeostasis is vital for human health.

Reduced insulin signaling maintains electrical transmission in a neural circuit in aging flies

Synapses undergo age-associated morphological and functional changes in a number of model organisms and in humans. In the fruit fly Drosophila melanogaster and the worm Caenorhabditis elegans, synaptic changes were seen during normal aging in both central and peripheral parts of the nervous system and linked to cognition, memory, learning, locomotor, and homeostatic deficits.

The Neural Representation of Prospective Choice during Spatial Planning and Decisions

Goal-directed behaviour rests on being able to rapidly evaluate the potential consequences of future actions. For example, consider the neuronal processing required for planning a new route home when a road you normally take is closed

Red Tides

Red tides occur all over the world but the farthest north they have been detected in Alaska is Cook Inlet. They are large blooms of toxin producing dinoflagellates that may color the water a deep red. The key point is the production of toxin. Red tides can actually produce other colorations of the tides, but not all colored tides are necessarily toxic. The toxin is taken in by filter feeding animals and stored in their flesh.

Uncovering Zika

This research focuses on creating a novel rapid diagnostic test for Zika Virus NS1 protein using nanoribbon microfluidics.

The Molecular Basis for the Broad Substrate Specificity of Human Sulfotransferase 1A1

The cytosolic sulfotransferase (SULTs) family catalyzes the transfer of a sulfate group from the universal 3′-phosphoadenosine 5′-phosphosulfate (PAPS) donor to a wide variety of acceptor molecules bearing a hydroxyl or an amine group [1], [2], [3]. Sulfonation results in inactivation of the majority of acceptors, including neurotransmitters, steroid hormones and drugs, thus modulating their biological activity and rendering the product more soluble and readily excretable.

Pancreatic Cancer Cells during Metastatic Progression

Our research focused on the detection of premalignant pancreatic cancer via computational analysis of serum proteomic profiles.

Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation

Interleukin-6 (IL-6) is a pleiotropic cytokine with important functions in many physiological and pathophysiological conditions. IL-6 activates intracellular signaling cascades through a homodimer of the ubiquitously expressed β-receptor glycoprotein 130 (gp130) but first has to bind to its nonsignaling alpha receptor (IL-6R). The IL-6R is expressed in a cell- and tissue-specific manner and only found on hepatocytes and some leukocytes like neutrophils and T cells.

The Long-Range Effects on Locally Important Marine Resources

Kotzebue, Alaska, a tiny city perched on the Baldwin Peninsula, is thirty-three miles above the Arctic Circle. Kotzebue is bordered by the Kotzebue Sound to the west and the Hotham Sound to the east. These two bodies of water both join into the Chucki Sea.

Methods of Reusing Food Waste

The development of an algorithm through the assessment of nutrients in a recycled food supplement for canines.

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2018 ScienceBuzz Symposium

Click Here to go to the Conference Website

We are excited to announce the first annual ScienceBuzz Symposium, dedicated to middle and high school students. The conference and registration is completely free! Currently, the symposium date is June 9, 2018.

Pre-register for the symposium by visiting the conference website or clicking here. There are a limited number of seats and we expect to fill up quickly, so register ASAP. The event will include several internationally-renowned speakers, workshop sessions, company exhibitions, scholarships, and research presentations. 


The 2018 ScienceBuzz Symposium is the first, completely free conference exclusively for middle and high school students. Our theme for this year is “One Day of Powerful Talks.”

It will be hosted in Lehigh Valley, Pennsylvania, but will include students from around the state and nearby regions. The event will have national guest keynote speakers (including a Nobel Prize Laureate, the head of a leading scientific institution, college admissions officers, university professors, leaders in gifted education, and top biopharma executives). It will also include workshop sessions, student poster presentations, five research scholarship awards, organizational and company exhibitions, and unique networking opportunities.

To learn more about the symposium, agenda, and logistical details, visit our website at

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