Computer Science

Egocentric and allocentric representations in auditory cortex

A central role of the brain is to build a model of the world and objects within it that remains stable across changes in sensory input when we move. In hearing, this requires that an observer maintains the identification of an auditory object as they move through an environment.

Dynamic patterning by the Drosophila pair-rule network reconciles long-germ and short-germ segmentation

Like other arthropods, the fruit fly Drosophila melanogaster has a segmented body plan. This segmental pattern is laid down in the embryo during the first 3 hours of development.

Developing a New Search for Randomly Accessible Data

There are only two widely-used searches for randomly accessible data: linear search and binary search. I developed and created a new search and tested it against binary search, linear search, and variations of them.

Digital Health: Tracking Physiomes and Activity Using Wearable Biosensors Reveals Useful Health-Related Information

Physiological parameters such as heart rate (HR), blood pressure, and body temperature can provide critical information about the physical health status of a person. Elevation of any of these parameters can be of concern; elevated HR and blood pressure are associated with cardiovascular disease, and elevated body temperature occurs during pathogen infection and inflammation [1–4]. Peripheral capillary oxygen saturation (SpO2) is a measure of oxygen saturation of hemoglobin in the blood, and patients with chronic pulmonary disease often have lower resting SpO2 and are required to use supplementary oxygen to attain a more optimal SpO2

Brain–Computer Interface–Based Communication in the Completely Locked-In State

Communication is the process of expressing and sharing feelings, thoughts, and intentions with one another by verbal and various nonverbal means. Communication skills appear automatic but can pose severe challenges to individuals suffering from motor neuron disorders. The most devastating of motor neuron diseases is amyotrophic lateral sclerosis (ALS) [1], which is progressive and renders an individual motionless, severely affecting his or her communication ability [2].

Automatic Compilation from High-Level Biologically-Oriented Programming Language to Genetic Regulatory Networks

Synthetic biology is an emerging field at the interface of biology, engineering, and physical sciences, which focuses on the systematic design and engineering of biological systems [1]–[3]. This field brings a set of new approaches for tackling biological problems and at the same time addresses real world problems.

Breast Cancer Metadata Collection

This study is the first to apply deep learning to analyze tumor-associated stroma, discovering novel diagnostic biomarkers for breast cancer.

A Shifting Mutational Landscape in 6 Nutritional States: Stress-Induced Mutagenesis as a Series of Distinct Stress Input–Mutation Output Relationships

The notion of stress-induced mutagenesis (SIM) [1,2] has changed our perspective on the flexibility of mutation rates in organisms. The earliest evidence for SIM was that starvation can increase the supply of mutations, presumably increasing the capacity for adaptive changes and evolvability [1,3,4]. SIM is a collection of mechanisms observed in bacterial, yeast, and human cells, in which mutagenesis pathways are activated in response to adverse conditions, such as starvation or antibiotic stresses [5,6].

A Mechanism for the Cortical Computation of Hierarchical Linguistic Structure

Detecting relevant signals in the environment is a crucial function in biological systems. For humans, language is a critical, if not the defining, species-specific environmental signal to detect. As such, it is not surprising that the human auditory system is specialised for speech processing [e.g., 1,2].

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