Pancreatic Cancer Cells during Metastatic Progression
Our research focused on the detection of premalignant pancreatic cancer via computational analysis of serum proteomic profiles.
Health/Medicine
Diabetic Retinopathy via Hypertensive Modeling
This interdisciplinary study develops a novel prognostic for Diabetic Retinopathy (DR) by modeling hypertensive changes at arterial-venous (AV) crossings
Cancer Stem Cells in Oral Squamous Cell Carcinoma
Oral Squamous Cell Carcinoma (OSCC) is a cancer of the mouth epithelium with an annual incidence rate in the US of nearly 48,000 cases annually and a 5-year survival rate of only 65%. Cancer stem cells (CSCs) are believed to be responsible for progression of OSCC. The project’s main goal is to observe the effect of Wnt/β-catenin signaling inhibition on oral squamous cell carcinoma.
Unraveling Complexities of Alzheimer’s Disease
Alzheimer’s is a neurodegenerative disease characterized by the formation of extracellular amyloid-beta (abeta or AB) plaques and intracellular tau plaques. This experiment explores whether the presence of normal tau-441 protein augments AB-42 aggregation.
Gene Involvement in Sensorineural Hearing Loss
Sensorineural hearing loss is a serious impairment that deprives more than 360 million people worldwide from one of their vital senses. Though common, this medical disability has no cure yet. However, gene therapy is an emerging treatment that is being developed to tackle the root causes of this morbidity.
Constructing Silver Nanoparticles
Each year, over two million new cases of skin cancer are diagnosed, which is greater than the combined incidence of cancers of the breast, prostate, lung and colon. Therefore, prevention of skin cancer from the harmful effects of UV remains a priority area of research.
Platelet-Dependent Killing of C. albicans
There are around 150,000-400,000 platelets per microliter of blood in a healthy human being (Williams, n.d.), each which are around two microns in size (“Platelets on the Web,” n.d.). Platelets are blood cells which assist in the clotting of blood vessels, a process also known as hemostasis.
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