Health/Medicine

Translational Genomics of Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) does not respond to receptor targeted treatments because they do not possess the ligands to bind to these receptors. Thus, more research needs to be explored in terms of the translational modifications that genes undergo during this disease.

Diabetic Retinopathy via Hypertensive Modeling

This interdisciplinary study develops a novel prognostic for Diabetic Retinopathy (DR) by modeling hypertensive changes at arterial-venous (AV) crossings

Cancer Stem Cells in Oral Squamous Cell Carcinoma

Oral Squamous Cell Carcinoma (OSCC) is a cancer of the mouth epithelium with an annual incidence rate in the US of nearly 48,000 cases annually and a 5-year survival rate of only 65%. Cancer stem cells (CSCs) are believed to be responsible for progression of OSCC. The project’s main goal is to observe the effect of Wnt/β-catenin signaling inhibition on oral squamous cell carcinoma.

Unraveling Complexities of Alzheimer’s Disease

Alzheimer’s is a neurodegenerative disease characterized by the formation of extracellular amyloid-beta (abeta or AB) plaques and intracellular tau plaques. This experiment explores whether the presence of normal tau-441 protein augments AB-42 aggregation.

Gene Involvement in Sensorineural Hearing Loss

Sensorineural hearing loss is a serious impairment that deprives more than 360 million people worldwide from one of their vital senses. Though common, this medical disability has no cure yet. However, gene therapy is an emerging treatment that is being developed to tackle the root causes of this morbidity.

Constructing Silver Nanoparticles

Each year, over two million new cases of skin cancer are diagnosed, which is greater than the combined incidence of cancers of the breast, prostate, lung and colon. Therefore, prevention of skin cancer from the harmful effects of UV remains a priority area of research.

Platelet-Dependent Killing of C. albicans

There are around 150,000-400,000 platelets per microliter of blood in a healthy human being (Williams, n.d.), each which are around two microns in size (“Platelets on the Web,” n.d.). Platelets are blood cells which assist in the clotting of blood vessels, a process also known as hemostasis.

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