Multidrug Resistant Superbugs
Antibiotics have been extensively used to treat patients with infectious diseases for the last 70 years. As these drugs have been used widely for long time, the organisms the antibiotics are designed to kill have adapted to them, making the drugs less effective. This can be prevented through selective separation, identification and eradication using fluorescent, magnetic multifunctional carbon dots.
Building Low-Cost Prosthetics
Building low-cost prosthetics by SLAM scanning the residual limbs of amputees.
Powering Wearable Microelectronics
Wearable low power biometric devices and body sensor network systems (BSNs) such as heart, respiration, and activity monitors are popular devices that are predicted to increase tenfold by 2018. This project focused on biomechanical energy harvesting from rib cage expansion using piezoelectric materials and frequency up conversion to power wearable microelectronics.
Cancer Stem Cells in Oral Squamous Cell Carcinoma
Oral Squamous Cell Carcinoma (OSCC) is a cancer of the mouth epithelium with an annual incidence rate in the US of nearly 48,000 cases annually and a 5-year survival rate of only 65%. Cancer stem cells (CSCs) are believed to be responsible for progression of OSCC. The project’s main goal is to observe the effect of Wnt/β-catenin signaling inhibition on oral squamous cell carcinoma.
Translational Genomics of Triple-Negative Breast Cancer
Triple-negative breast cancer (TNBC) does not respond to receptor targeted treatments because they do not possess the ligands to bind to these receptors. Thus, more research needs to be explored in terms of the translational modifications that genes undergo during this disease.