Osteosarcoma, a bone tumor of childhood, is lethal when unresponsive to chemotherapy. ER stress response, a cell survival mechanism that is triggered upon exposure to stressors such as chemotherapy, is one of the ways a tumor becomes resistant to chemotherapy. This project explores novel methods of producing a noncytotoxic EGFP-ATF6 construct to signal Endoplasmic Reticulum stress response.
Building low-cost prosthetics by SLAM scanning the residual limbs of amputees.
This interdisciplinary study develops a novel prognostic for Diabetic Retinopathy (DR) by modeling hypertensive changes at arterial-venous (AV) crossings
Our research focused on the detection of premalignant pancreatic cancer via computational analysis of serum proteomic profiles.
RNA-based viruses and bacteria have been sources of large-scale epidemics and pandemics, most notably Ebola, SARS, influenza, hepatitis C, HIV, and the Zika Virus. Normal detection of these biological agents requires multiple lab processes. This project aims to develop a fully integrated lab-on-a-chip device to accomplish this.
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